The Effect of Anemia on Breath Tests

Posted by Lawrence Taylor on February 25th, 2005

I have commented repeatedly in the past about the inaccuracy and unreliability of breath-testing devices used in DUI investigations. This is due to a wide range of factors: inherent design defects (see, for example, my previous post "Why Breathalyzers Don’t Measure Alcohol"); ineffective calibration and maintenance of the machines; improper administration of the test; radio frequncy interference; and, most importantly, physiological variability in humans.

The main problem with breath machines is that they are designed to assume all human beings are the same (see "Convicting the ‘Average’ DUI Suspect"). In fact, we are all very different from one another in ways that are critical to such testing — and we are ourselves physiologically different from one moment to the next. Each of us, for example, is inherently different in our partition ratio — the ratio of alcohol in our breath compared to alcohol in our blood — and this ratio differs within ourselves from hour to hour (see "Breathalyzers — and Why They Don’t Work").This is critical, as the breathalyzer will automatically compute the amount of alcohol in the blood based upon the measured alcohol on the breath — using a uniform ratio that (falsely) assumes we are all the same.

Another human variable is the existence of such conditions as diabetes (see "Diabetes and the Counterfeit DUI"), acid reflux ("GERD, Acid Reflux and False Breathalyzer Results")…. and anemia. A person suffering from anemia has a low red blood cell count, perhaps half as much as would be normal. Put simply, when there are fewer red blood cells, the body will increase the amount of plasma to fill the void. Red and white blood cells are solid; plasma is liquid. Alcohol is attracted to liquid in the body, not muscle, bone, or other solids. It follows that the higher the ratio of liquid to solids in the blood (called the hematocrit), the higher the amount of alcohol in the blood — and the higher will be the reading on the breathalyzer. The male-female average hematocrit is 45% (men average 47%, women 42%), but the range varies for men from 42 to 52%, and for woman from 37 to 47%. The machine, of course, assumes that all suspects have a hematocrit of 45%.

The effect of an individual’s hematocrit on breath analysis can be mathematically computed. The partition ratio of alcohol in blood to alcohol in breath uniformly used in breath testing is 2100:1. If the suspect’s hematocrit is, say, 54%, the breath test result could be computed by multiplying it by 45/54. Assuming a breath test result of .11%, for example, the true blood-alcohol concentration could be determined by the formula .11 x 45/54 = .09%. In other words, a person with a true BAC of .09% but a hematocrit of 54% would test on an otherwise "accurate" machine as .11%. Just because he/she is anemic — or simply varies from the statistical norm.

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  1. […] As I have said in earlier posts, law enforcement investigation techniques depend largely upon the premise that all humans are physiologically identical (see “Convicting the Average DUI Suspect“). Without that presumption, field sobriety and breath alcohol tests would not be possible. Unfortunately, the premise is always false. I’ve written about many examples of physiological differences — from person to person and within one person from moment to moment — which will directly alter breath or blood alcohol testing (see, for example, “Diabetes and the Counterfeit DUI“, “GERD, Acid Reflux and False Breathalyzer Results“, “The Effect of Anemia on Breath Tests” and “Do Breathalyzers Discriminate Against Women?“). Yet another example of variability is body temperature. Put simply, an individual’s body temperature will have a direct effect on the results of a breath test. The effects of changes in body temeprature from the norm of 98.6 degrees on breath testing has been discussed in an article entitled “Body Temperature and the Breathalyzer Boobytrap”, 721 Michigan Bar Journal (September 1982). If because of illness, for example, the body temperature is elevated by only 1 degree Centrigrade (1.8 degrees Fahrenheit), the 1:2100 breath-to-blood partition ratio used by breathalyzers will be altered so as to produce a 7 percent higher test result. Higher body temperatures will, of course, result in even greater errors. Dr. Michael Hlastala, Professor of Physiology, Biophysics and Medicine at the University of Washington, confirms this. In an article entitled “Physiological Errors Associated with Alcohol Breath Testing”, 9(6) The Champion 18 (1985), he notes that even the average body temperature of a normal, healthy person “may vary by as much as 1 degree Centigrade above or below the normal mean value of 37 degrees Centigrade — or 1.8 degrees from the mean value of 98.6 degrees Fahrenheit”. Not only can the normal mean body temperature of an individual vary from that of other persons, but the “temperature of any individual may vary from time to time during the day by as much as 1 degree Centigrade”. Result? The partition ratio for alcohol in blood is altered — meaning, according to Professor Hlastala, a 6.3 percent error for every 1 degree Centigrade increase or decrease from the presumed normal body temperature. Yet another example of how breathalyzers are not actually testing you. Instead, they are testing an “average” person who does not exist. But you are the one who gets convicted. Share: […]

    Pingback by DUI BLOG : Bad Drunk Driving Laws, False Evidence and a Fading Constitution — December 11, 2006 @ 2:32 pm

  2. […] I mentioned in my previous post that the single greatest flaw in so-called “breathalyzers” is that they are designed to assume that all humans are physiologically identical. This is, of course, a false assumption, and I have mentioned examples in other posts of erroneous breath analysis attributable to human variability. In the coming days, I will take a look at some further examples. Let’s take a look at one….. […]

    Pingback by DUI BLOG : Bad Drunk Driving Laws, False Evidence and a Fading Constitution — December 21, 2006 @ 12:30 pm

  3. […] All states now have two drunk driving laws: (1) driving under the influence of alcohol (aka “DUI”, with local variations, such as “driving while intoxicated” or “DWI”), and (2) the so-called per se law of driving with .08% or higher blood-alcohol concentration (BAC). Most of those arrested will be charged and prosecuted for both offenses. The breath machines (commonly — and inaccurately — referred to as “Breathalyzers”) used to obtain the BAC are, obviously, critical to the drunk driving case. As for the per se offense, the only evidence of the crime is the machine: if the thing says .08% or higher and the jury believes it, the defendant is guilty. And even as to the DUI charge, the readings will be considered presumptive: if the BAC is .08% or higher, the jury will be instructed by the judge that the defendant is presumed guilty — and he must be found guilty unless he can prove his innocence (I’ve discussed this in “Whatever Happened to the Presumption of Innocence?“). These machines are all-important: they determine guilt or innocence. But their manufacturers continue to assure us that they are “state of the art”. So how accurate are they? Well, as I’ve written in the past, not very: Breathalyzers — and Why They Don’t Work Close Enough for Government Work The Mouth Alcohol Problem Breathalyzers: Why Aren’t They Warranted to Measure Alcohol? Driving Under the Influence of….Bread? Warning: Breathalyzer in Use Breath Fresheners and Breathalyzers Diabetes and the Counterfeit DUI Why Breathalyzers Don’t Measure Alcohol Can Body Temperature Affect Breathalyzer Results? The Effect of Anemia of Breath Tests GERD, Acid Reflux and False Breathalyzer Results Driving Under the Influence of….Gasoline? Do Breathalyzers Discriminate Against Women? Breathalyzer Inaccuracy: Testing During the Absorptive State Breathalyzer Inaccuracy: Post-Absorptive Breathalyzer Inaccuracy….It Gets Worse Warning: Smoking Can be Hazardous to Breathalyzer Results How to Fool the Breathalyzer Breathalyzer Manufacturers Won’t Tell How They Work […]

    Pingback by DUI BLOG : Bad Drunk Driving Laws, False Evidence and a Fading Constitution — January 19, 2007 @ 4:11 pm

  4. […] Why Breathalyzers Don’t Measure Alcohol Can Body Temperature Affect Breathalyzer Results? The Effect of Anemia of Breath Tests GERD, Acid Reflux and False Breathalyzer Results Driving Under the Influence of….Gasoline? […]

    Pingback by DUI BLOG : Bad Drunk Driving Laws, False Evidence and a Fading Constitution — February 15, 2009 @ 10:54 am


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